UNDERSTANDING PROTEIN STRUCTURE DETERMINATION
September 1-6, 1996
Preliminary Programme
SUNDAY, Sept. 1
14.00 - 16.00Registration and mounting of posters
16.00Welcome
16.05J. Drenth
Introduction to protein X-ray crystallography I
16.50O. Jardetzky
Introduction to protein NMR spectroscopy
18.00Buffet dinner, Nova Park Hotel
MONDAY, Sept. 2
9.00J. Drenth
Introduction to protein X-ray crystallography II
9.45Coffee
10.15D. Neuhaus
The NOE and the ROE; physical basis and measurement
11.00T. James
Three-dimensional structure derivation from NMR data
12.00Lunch
14.00H.D. Bartunik
Phase determination from anomalous X-ray diffraction
14.45K. Moffat
Time-resolved macromolecular crystallography
using synchrotron X-ray sources
15.30Coffee
16.00J. Navaza
Assembling crystals from known molecular models
18.00Reception at the Stockholm City Hall
on invitation by the Stockholm City Council
TUESDAY, Sept. 3
9.00J. Johnson
Experimental and computational solutions to the virus
crystallography phase problem
9.45A. Jones
Building a model in an electron density map
10.30Coffee
10.50M. Clore
Determination of structures of larger proteins, protein-protein and protein-DNA complexes by multidimensional NMR
12.00Lunch
14.00G.Vriend
Improving structures using statistical and data base techniques
14.45R. Read
Improved structure refinement through maximum likelihood
15.30Coffee
Poster session
17.00Beer and sandwiches, continued poster session
WEDNESDAY, Sept. 4
9.00A. Palmer
NMR studies of protein dynamics
9.45Coffee
10.15O. Jardetzky
Precision is not accuracy: effects of dynamics on protein structure determination by NMR
11.00G. Kleywegt
Why protein crystallographers shouldn’t be so arrogant...
12.00Lunch

No afternoon programme
THURSDAY, Sept. 5
9.00S. Cusack
Crystallographic studies of protein-RNA complexes
9.45Coffee
10.15K. Wüthrich
NMR studies of the solvation of proteins and nucleic acids in solution
11.00W. Chazin
Putting it all together: Comprehensive study of a protein's structure and dynamics by NMR
12.00Lunch
14.00 - 16.00Round-table discussion
Moderators: J. Drenth and K. Wüthrich
17.30Boat trip departure from Stockholm City, with Dinner
FRIDAY, Sept. 6 Late morning start!
9.45Coffee
10.15P. Timmins
Neutron scattering studies of proteins
and multi-component proteins
11.00R. Henderson
Title to be announced
11.45Conclusion
12.00Lunch